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. 2007 Aug 30;1(1):e72. doi: 10.1371/journal.pntd.0000072

Table 4. Analysis of the Relationship of β-tubulin Genotype with Patient and Parasitological Independent Variables After Treatment.

N = 98 female worms OR 95% CI p
150 µg/kg three-monthly 2.22 0.39–12.65 0.370
800 µg/kg yearly 0.93 0.22–3.94 0.923
800 µg/kg three-monthly 1.68 0.23–12.15 0.609
Age of patient 1.00 0.94–1.04 0.691
No. females/nod 0.83 0.57–1.23 0.356
CMFL 41–60 mf/ss 6.24 1.09–35.59 0.039
CMFL 61–70 mf/ss 4.44 0.91–21.54 0.065
CMFL 71–114 mf/ss* - - -
No. nod. 1994 0.88 0.68–1.13 0.305

Odds ratios (OR) and 95% confidence intervals (95% CI.) for logistic regression of heterozygote status (vs. homozygote) of worms collected after ivermectin treatment on five independent variables. No. females/nod. = total number of females in the nodule; No. nod. 1994 = total number of palpable nodules in 1994; CMFL = Community Microfilarial Load (reference category: 10–40 microfilariae per skin snip (mf/ss)). Reference category for treatment group: 150 µg/kg yearly.

*

All worms from villages with CMFL 71–114 mf/ss were heterozygotes; consequently, the highest CMFL category was not used for the estimation of other independent variables.