Table 4. Analysis of the Relationship of β-tubulin Genotype with Patient and Parasitological Independent Variables After Treatment.
N = 98 female worms | OR | 95% CI | p |
150 µg/kg three-monthly | 2.22 | 0.39–12.65 | 0.370 |
800 µg/kg yearly | 0.93 | 0.22–3.94 | 0.923 |
800 µg/kg three-monthly | 1.68 | 0.23–12.15 | 0.609 |
Age of patient | 1.00 | 0.94–1.04 | 0.691 |
No. females/nod | 0.83 | 0.57–1.23 | 0.356 |
CMFL 41–60 mf/ss | 6.24 | 1.09–35.59 | 0.039 |
CMFL 61–70 mf/ss | 4.44 | 0.91–21.54 | 0.065 |
CMFL 71–114 mf/ss* | - | - | - |
No. nod. 1994 | 0.88 | 0.68–1.13 | 0.305 |
Odds ratios (OR) and 95% confidence intervals (95% CI.) for logistic regression of heterozygote status (vs. homozygote) of worms collected after ivermectin treatment on five independent variables. No. females/nod. = total number of females in the nodule; No. nod. 1994 = total number of palpable nodules in 1994; CMFL = Community Microfilarial Load (reference category: 10–40 microfilariae per skin snip (mf/ss)). Reference category for treatment group: 150 µg/kg yearly.
All worms from villages with CMFL 71–114 mf/ss were heterozygotes; consequently, the highest CMFL category was not used for the estimation of other independent variables.