. Author manuscript; available in PMC: 2008 Apr 30.

Published in final edited form as: Neurotoxicology. 2007 Feb 11;28(3):664–671. doi: 10.1016/j.neuro.2007.02.002

Table 1.

Interventions for Experimental Groups

	Group I (n=10)	Group II (n=7)	Group III (n=5)	Group IV (n=4)
Anesthesia	Isoflurane	Isoflurane	Isoflurane	None
FIO₂ during experiment	100%	Titrated to PAO₂ of 100–115mmHg	Titrated to PAO₂ of 100–115mmHg	100%
Pharmacologic Paralysis	None	None	Gallamine	None
Mechanical Ventilation	None	At apnea	Throughout experiment	None
1hour survival	0/10	5/7	4/6	0/4
Functional Measurements	ETCO2, Vi, Ve, esophageal pressure, arterial pressure, pulse oximetry, PaO₂, PaCO₂	ETCO2, Vi, Ve, esophageal pressure, arterial pressure, pulse oximetry, PaO₂, PaCO₂	ETCO2, Vi, Ve, arterial pressure, pulse oximetry, PaO₂, PaCO₂	ETCO2, Vi, Ve

FIO₂ - fraction of inspired oxygen

ETCO2 - end tidal carbon dioxide

Vi - volume of inspired gas

Ve – volume of expired gas

PaO₂ – arterial partial pressure of oxygen

PaCO₂ – arterial partial pressure of carbon dioxide