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The effect of Mn on cell cycle progression*
| Control | Mn-treated | p-value | |
|---|---|---|---|
| G1 | 55.8±0.9 | 36.7±1.3 | 0.0003 |
| S | 36.3±1.1 | 54.9±1.3 | 0.0003 |
| G2 | 3.8±0.7 | 4.5±0.2 | 0.57 |
Primary human astrocytes treated with no reagent (control) or 200 μM MnCl2 (Mn-treated) for 7 days were subjected to flow cytometric analysis as described in Materials and Methods. The shown data are averages from three experiments, and the two-tailed t-test p-value was calculated by using the SAS software.
