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. Author manuscript; available in PMC: 2007 Oct 24.
Published in final edited form as: J Biol Chem. 2000 Dec 7;276(11):7899–7905. doi: 10.1074/jbc.M008262200

Table II. Induction of NO production by IL-12 p70 and IL-12 p402 in mouse primary astrocytes, microglia, and macrophages.

Mouse peritoneal macrophages and primary astrocytes and microglia were cultured for 24 h in serum-free DMEM/F-12 with the listed reagents. Nitrite concentration in the supernatants was measured as described under “Materials and Methods.” Data are mean ± S.D. of three different experiments.

Nitrite, nmol/mg/24 h
Treatments
Macrophages Astrocytes Microglia
Control 9.2 ± 1.2 3.4 ± 0.3 6.7 ± 0.8
IL-12 (5 ng/ml) 112 ± 13.5 3.5 ± 0.4 92.5 ± 11.2
p402 (5 ng/ml) 120 ± 15 3.4 ± 0.4 95.2 ± 10.8