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. Author manuscript; available in PMC: 2007 Oct 24.
Published in final edited form as: J Immunol. 1995 May 15;154(10):5282–5292.

FIGURE 4.

FIGURE 4

A drVV expressing IL-2,. but not GM-CSF, IFN-γ, or TNF-α, significantly reduces the number of pulmonary metastases in a 3-day model. Five BALB/c mice per group were injected i.v. with 5 × 105 tumor cells of either CT26.WT or CT26.CL25 cell lines. Three days later they received a single i.v. injection of HBSS alone (none) or containing 5 × 106 PFU/mouse of different rVV, as indicated. On day 12 post tumor challenge, lungs were harvested and pulmonary nodules were enumerated in a blind fashion. An independent repeat of this experiment gave identical results.