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. 2007 Oct 19;3(10):e184. doi: 10.1371/journal.pgen.0030184

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© 2007 Han et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The DNA template used in each reaction is listed on top of the gel chromatograph (M, 100-bp ladder; H, human; C, chimpanzee; G, gorilla; O, orangutan). The large and small sizes of PCR products indicate two Alu elements and one Alu element, respectively. The thunderbolts represent recombination events between two Alu elements, causing ARMDs. Possible scenarios that explain the observed chromatograph: (A) chimpanzee-specific ARMDs, (B) incomplete lineage sorting of an ARMD event, and (C) parallel independent ARMD events.