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. Author manuscript; available in PMC: 2008 Oct 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2007 Jul 4;224(1):39–48. doi: 10.1016/j.taap.2007.06.019

Fig. 1.

Fig. 1

Immunostaining for HKII expression in the kidneys of control mice (A & B), and mice exposed to 10 ppb arsenic (C), and 50 ppb arsenic for 21 days. Tissue sections were probed with a HKII isoform specific antibody and matched HRP-linked secondary antibody, then developed with metal enhanced DAB and counterstained with nuclear fast red. HKII appears as dark grey to black staining within the glomeruli. The cytoplasm appears light grey, and the counterstained nuclei as the slightly darker round inclusions (arrow a). Arrow b indicates the location of an individual glomerulus for reference.