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Tumorigenicity assay of MCF7 cells treated with inhibitors in nude mice
| Cell number for injection |
||
|---|---|---|
| 1.5 × 106 | 1.5 × 105 | |
| Control cells | 5/5 | 4/5 |
| Rapamycin-treated cells | 2/5 | 2/5 |
| LY 294002-treated cells | 2/5 | 1/5 |
| IS3 295-treated cells | 2/5 | 2/5 |
MCF7 cells were treated with LY294002 (2.5 μM), rapamycin (5 μM), and IS3 295 (10 μM) for 3 days.
