Table 1.

Transgene integration and expression in tails from transgenic mice of independent lines

Sequence	Line	Copy number	CAT activity
(GRE)2	5	2	220  ±  8 (13)
	6	1	No expression
	7	2	No expression
	35	2	127  ±  10 (10)
GRUs	28	2	No expression
	29	2	211  ±  35 (5)
	33	5	389  ±  50 (4)
	40	1	No expression
	41	2	103  ±  23 (3)

Copy number was estimated by both slot-blot and Southern blot analyses of mouse tail DNA. The CAT activity (pmol of chloramphenicol acetylated per min per μg of protein) (mean ± SEM) measured in the tail is indicated; number of mice analyzed is in parentheses.