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. 2006 Dec 11;150(2):136–142. doi: 10.1038/sj.bjp.0706985

Figure 4.

Figure 4

Intracellular signalling associated with insulin-induced airway smooth muscle contraction. Insulin (1 μM)-induced contractions were recorded in the absence and presence of LY-294002 (10 μM), PD 98059 (30 μM), U-0126 (3 μM) or Y-27632 (1 μM). Responses shown in (b) are corrected for inherent myogenic tone and are derived from the data shown in (a). All data shown represent means and s.e.m. (vertical lines) of five to six experiments, each performed in duplicate, obtained using five to six different animals. *P<0.05; ***P<0.001 compared to control. #P<0.05 compared to the control insulin response.