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Maximal histamine-induced contractions are independent of Rho-kinase (a), p42/44-MAPK (b) and PI-3-kinase (c). Data represent means and s.e.m. (vertical lines) of five to seven experiments, each performed in duplicate, obtained using five to seven different animals. Maximal histamine-induced contraction amounted to 1.53±0.1 g on average.
