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Dose–response curves for the effects of i.pl. injection of PAR4-activating peptide (PAR4-AP) (AYPGKF) or control peptide (YAPGKF) on withdrawal latency in response to a thermal stimulus (a) and on nociceptive threshold in response to a mechanical stimulus (b) (observed at 60 min). Each symbol represents the mean and vertical lines show s.e.m. (n=8 rats per group).
