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. Author manuscript; available in PMC: 2008 Sep 7.
Published in final edited form as: Brain Res. 2007 Jul 17;1168:46–59. doi: 10.1016/j.brainres.2007.06.066

Figure 2.

Figure 2

Glial fibrillary acidic protein immunoreactivity (GFAP-IR) is increased in satellite cells surrounding sensory neurons in the L4 dorsal root ganglia (DRG) of rats following intravenous paclitaxel administration. L4 DRG sections from vehicle (cremephor/ethanol) (A) and paclitaxel-treated rats (B-D) were examined immunohistochemically with an antibody against GFAP, an intermediate filament present in DRG satellite cells. Increased GFAP-IR was observed at day 6 (C) and day 10 (D) following paclitaxel administration. DRG sections from paclitaxel treated rats at day 4 (B) or earlier time points displayed similar levels of GFAP-IR compared to vehicle-treated rats (A). Scale bars A-D = 30 μm.