Table 2.
Tissue distribution of PLGA microspheres after intramuscular administration
| 1d | 7d | 15d | 30d | 60d | 120d | |
| L Node | 4 | 5 | 2 | 4 | 0 | 2 |
| B Marrow | 3 | 1 | 2 | 1 | 2 | 2 |
| Spleen | 5 | 3 | 2 | 2 | 0 | 1 |
| Thymus | 3 | 2 | 1 | 3 | 4 | 2 |
| Lung | 4 | 5 | 5 | 3 | 0 | 2 |
| Kidney | 4 | 3 | 3 | 0 | 5 | 0 |
| Liver | 5 | 2 | 3 | 0 | 5 | 2 |
| Testicles | 2 | 4 | 5 | 2 | 5 | 2 |
The numbers in the columns indicate the number of the animals that presented positive detection of fluorescent microspheres in each organ evaluated at 1, 7, 15, 30, 60 (n = 5 mice) and 120 (n = 3 mice) days after intramuscular administration.