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Activities of ofloxacin and ciprofloxacin for derivatives of E. faecalis JH2-2
| E. faecalis derivative | Characteristic | MIC (μg/ml)
|
|
|---|---|---|---|
| Ofloxacin | Ciprofloxacin | ||
| JH2-2 | Control | 3 | 1.5 |
| JH2-2ΩpG1KT | qnr inactivation | 1.5 | 0.75 |
| JH2-2ΔpG1KT | Spontaneous loss of pG1KT | 3 | 1.75 |
| JH2-2/pORI23 | Control | 3.5 | 2 |
| JH2-2ΩpG1KT/pORI23::qnr-cat | qnr complementation | 32 | 8 |
| JH2-2/pORI23::qnr-cat | qnr overexpression | 32 | 8 |
