TABLE 2.

Frequency of main outcomes during intervention period (3 to 18 months of age)

Outcome	Placebo group			SP group			% PE (95% CI)	P
	No. of events	PYARa	Incidence density (no. of events/PYAR)	No. of events	PYAR	Incidence density (no. of events/PYAR)
Malaria
All episodes	729	627.0	1.16	571	630.3	0.91	22.5 (11.8-31.9)	<0.0001
Episodes with ≥5,000 parasites/μl	393	646.4	0.61	324	644.6	0.50	17.7 (2.0-30.9)	0.03
Severe malaria	15	668.2	0.02	12	662.6	0.02	19.3 (−72.4-62.2)	0.58
Anemia
Hb of <7 g/dl	283	641.2	0.44	215	639.1	0.34	23.6 (4.1-39.1)	0.02
Hb of <7 g/dl plus asymptomatic parasitemia	164	659.6	0.25	108	657.0	0.16	34.0 (13.1-49.9)	0.003
Other
Hospitalizationb	240	655.2	0.37	166	653.7	0.25	31.3 (2.9-51.4)	0.03
Outpatient attendance	2,294	536.8	4.27	2,140	540.0	3.96	7.2 (−0.5-14.4)	0.07
Asymptomatic parasitemia	389	646.6	0.60	260	648.3	0.40	33.7 (21.1-44.3)	<0.0001
Nonmalarial fever	285	652.6	0.44	269	647.7	0.42	4.9 (−12.4-19.5)	0.56
Death	23	675.9	0.03	22	669.8	0.03	−0.7 (−81.9-44.2)	0.98

^aPYAR, person-years at risk.

^bAdmission by study physician or respective history.