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Adverse events in the two treatment groups (intention-to-treat analysis)
| Adverse event | No. (%) of occurrences ina:
|
P value | |
|---|---|---|---|
| Doxycycline group | Azithromycin group | ||
| All | 40 (27.6) | 16 (10.6) | <0.001 |
| Nausea | 3 (2.1) | 1 (0.7) | |
| Vomiting | 22 (15.2) | 10 (5.9) | |
| Nausea and vomiting | 10 (6.9) | 1 (0.7) | |
| Diarrhea | 1 (0.6) | 1 (0.7) | |
| Abdominal pain | 1 (0.6) | 0 | |
| Rash | 1 (0.6) | 3 (0.2) | |
| Dizziness | 2 (1.2) | 0 | |
For the doxycycline group, n = 145; for the azithromycin group, n = 151.
