. 2007 Jul 2;51(9):3240–3246. doi: 10.1128/AAC.00157-07

TABLE 2.

Distributions of phenotypes, genotypes, and antimicrobial resistance patterns of 125 erythromycin-resistant S. pneumoniae isolates

Phenotype^a (no. of isolates)	MIC range (μg/ml)			Resistance pattern^b	No. of isolates	No. of isolates with resistance determinant
Phenotype^a (no. of isolates)	Erythromycin	Clindamycin	Josamycin	Resistance pattern^b	No. of isolates	erm(B)	mef(E)	mef(A)	tet(M)
Constitutive MLS_B (91)	>32	>0.5	>2	Pen^r Ery^r Cli^r Jos^r Chl^r SxT^r Tet^r	26	26	1	0	26
				Pen^r Ery^r Cli^r Jos^r Chl^s SxT^r Tet^r	23	23	1	0	23
				Pen^r Ery^r Cli^r Jos^r Chl^s SxT^s Tet^r	13	13	0	0	13
				Pen^s Ery^r Cli^r Jos^r Chl^r SxT^r Tet^r	8	8	1	0	8
				Pen^s Ery^r Cli^r Jos^r Chl^s SxT^s Tet^r	8	8	1	0	8
				Pen^s Ery^r Cli^r Jos^r Chl^s SxT^r Tet^r	5	5	0	0	5
				Pen^s Ery^r Cli^r Jos^r Chl^s SxT^s Tet^s	3	3	0	0	0
				Pen^r Ery^r Cli^r Jos^r Chl^s SxT^r Tet^s	2	2	1	0	1
				Pen^r Ery^r Cli^r Jos^r Chl^s SxT^s Tet^s	1	1	0	0	0
				Pen^r Ery^r Cli^r Jos^r Chl^r SxT^s Tet^r	1	1	0	0	0
				Pen^r Ery^r Cli^r Jos^r Chl^r SxT^r Tet^s	1	1	0	0	0
Inducible MLS_B (18)	4->32	0.5->0.5	>2	Pen^r Ery^r Cli^r Jos^r Chl^r SxT^r Tet^r	5	5	0	0	5
				Pen^r Ery^r Cli^r Jos^r Chl^s SxT^r Tet^r	8	8	1	0	8
				Pen^r Ery^r Cli^r Jos^r Chl^s SxT^s Tet^r	2	2	0	0	2
				Pen^r Ery^r Cli^r Jos^r Chl^s SxT^s Tet^s	1	1	0	0	0
				Pen^s Ery^r Cli^r Jos^r Chl^r SxT^r Tet^r	1	1	0	0	1
				Pen^s Ery^r Cli^r Jos^r Chl^s SxT^r Tet^s	1	1	0	0	0
M (16)	2-32	≤0.25	≤0.5	Pen^r Ery^r Cli^s Jos^s Chl^s SxT^r Tet^s	6	0	6	0	0
				Pen^s Ery^r Cli^s Jos^s Chl^s SxT^s Tet^s	6	0	4	2	0
				Pen^r Ery^r Cli^s Jos^s Chl^s SxT^s Tet^s	2	0	2	0	0
				Pen^r Ery^r Cli^s Jos^s Chl^s SxT^s Tet^r	1	0	1	0	1
				Pen^r Ery^r Cli^s Jos^s Chl^r SxT^s Tet^s	1	0	1	0	0

According to the results of the double-disk diffusion method (6).

According to the results of the broth microdilution method.