TABLE 3.

Nonsynonymous mutations observed for P. malariae, P. brasilianum, P. falciparum, and P. vivax

Organism	Amino acid residuea											No. of isolates
	13	15	22	48	50	57	58	61	114	170	206
P. brasilianum	I	A	H	K	N	F	S	T	S	I	V	1
P. malariae
Haplotype 1	I	A	H	K	N	F	S	T	S	I	I	3b
Haplotype 2	I	A	H	K	N	F	S	T	G	I	I	1 (Viet Nam)
Haplotype 3	I	A	H	E	N	F	S	T	S	I	I	1 (Guinea-Bissau)
Haplotype 4	I	A	Q	K	N	F	S	T	S	I	I	26c
Haplotype 5	I	A	Q	K	N	F	S	T	N	I	I	2 (Thailand)
Haplotype 6	I	A	Q	K	K	F	S	T	S	I	I	1 (Lao PDR)
Haplotype 7	I	A	Q	K	N	F	S	T	S	M	I	1 (Viet Nam)
P. falciparum		16			51		59		108	164
		A-V			N-I		C-R		S-N/T	I-L
P. vivax	13					57	58	61	117	173
	I-L					F-L/T	S-R	T-M	S-N/T	I-L

^aResidues resulting from nonsynonymous mutations are indicated in boldface.

^bTwo from Viet Nam and one from Guinea-Bissau.

^cEighteen from Thailand, 4 from Lao PDR, 2 from Papua New Guinea, 1 from Viet Nam, and 1 from Guinea-Bissau.