TABLE 1.

MICs of imipenem and meropenem of P. aeruginosa isolates carrying ISPa26^a

Isolate	Yr of isolation	Hospital	Type of specimen	MIC (μg/ml)		ISPa26		PFGE profileb
				IPM	MPM	Copy no.	Inserted into oprD
1	2000	GSH	Blood	>32	>32	2	−	A
6	2000	GSH	Pus	>32	6	1	−	B
7	2000	GSH	Tracheal aspirate	>32	6	1	−	C
8	2000	GSH	Tracheal aspirate	>32	>32	3	+	C
12	2000	GSH	Tracheal aspirate	2	3	1	−	C
286	2004	GSH	CF sputum	>32	>32	2	−	C
529	2006	RCCH	CF sputum	1	2	1	−	C

^aIPM, imipenem; MPM, meropenem; GSH, Groote Schuur Hospital; RCCH, Red Cross War Memorial Children's Hospital; CF, cystic fibrosis; +, inserted into oprD; −, present in isolate but not inserted into oprD; PFGE, pulsed-field gel electrophoresis.

^bPFGE profiles designated using Tenover criteria (5).