FIG. 1.
Synthesis of CMX157. Synthesis of CMX157 was carried out as described previously for the alkoxyalkyl esters of (S)-HPMPA (3). Reagents: a, NaH and N,N-dimethylformamide, 50°C; b, 80% aqueous CH3COOH. Abbreviations: Tr, trityl, R, HDP.
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