TABLE 1.
Peptides used in this study
| Protein and peptide | Peptide sequencea | Species (Mka genotype)b |
|---|---|---|
| ESAT-6 | ||
| 1 | EAYQGVQQKWDATATE | M. bovis |
| 1A | --------------Q- | M. kansasii (I-V) |
| 2 | KWDATATELNNALQNL | M. bovis |
| 2A | ------Q--------- | M. kansasii (I-IV) |
| 2B | ------Q---S----- | M. kansasii (V) |
| 3 | LNNALQNLARTISEAG | M. bovis |
| 3A | --------S------- | M. kansasii (I-IV) |
| 3B | --S-----S------- | M. kansasii (V) |
| CFP-10 | ||
| 4 | QEAGNFERISGDLKTQ | M. bovis |
| 4A | ------------M--- | M. kansasii (IV) |
| 5 | IDQVESTAGSLQGQWR | M. bovis |
| 5A | --------A---A--- | M. kansasii (I-V) |
| 6 | GSLQGQWRGAAGTAAQAA | M. bovis |
| 6A | A---A------------- | M. kansasii (I-V) |
| 6B | A---A------A------ | M. kansasii (IV) |
| 7 | AGTAAQAAVVRFQEAANK | M. bovis |
| 7A | --A--------------- | M. kansasii (IV) |
| 8 | VVRFQEAANKQKQELDEI | M. bovis |
| 8A | ------------A--E-- | M. kansasii (I-V) |
| 9 | QKQELDEISTNIRQAGVQYS | M. bovis |
| 9A | --A----E--------------- | M. kansasii (I-V) |
| 10 | NIRQAGVQYSRADEEQQQ | M. bovis |
| 10A | ----------K------- | M. kansasii (I-V) |
a
-, amino acid residue in M. kansasii-derived peptide identical to the residue in the M. bovis sequence. Amino acids are represented by the one-letter code.
b
M. kansasii genotype according to Arend et al. (4).