TABLE 5.
Numbers of positive results obtained by different methods over the course of experimental infection with M. tuberculosis in NHP performed at MRL
| Method | No. positive/total (%) at postinoculation wk:
|
||||||
|---|---|---|---|---|---|---|---|
| 0 | 4 | 8 | 12 | 16 | 20 | 24 | |
| Skin testa | 0/17 (0) | 15/17 (88) | 7/17 (41) | 0/6 (0) | 0/6 (0) | 0/6 (0) | 0/6 (0) |
| PrimaTB STAT-PAK | 0/17 (0) | 3/17 (18) | 10/15 (67) | 11/11 (100) | 10/10 (100) | 10/10 (100) | 8/8 (100) |
| Tracheal wash culture | 0/17 (0) | 7/17 (41) | 8/17 (47) | 9/12 (75) | 5/7 (71) | 6/10 (60) | 5/8 (63) |
| Tracheal wash PCR | 0/17 (0) | 4/17 (24) | 5/17 (29) | 2/12 (17) | 1/9 (11) | 5/10 (50) | 4/8 (50) |
| Skin test + PrimaTB STAT-PAK | 0/17 (0) | 16/17 (94) | 14/17 (82) | 11/11 (100) | 10/10 (100) | 10/10 (100) | 8/8 (100) |
a
Starting at 12 weeks postinoculation, the skin test was performed only on the group of six infected cynomolgus monkeys.