TABLE 1.
The top 10 up-regulated and the top 10 down-regulated genes during early vegetative growth in A. nidulans
| Locus | A. nidulans annotation or best informative BLAST match (accession no.; E value)a | Fold change in expressionb |
|---|---|---|
| Up-regulated genes | ||
| AN8638.3 | Neosartorya fischeri hemerythrin HHE cation binding domain protein (XP_001261781; 1e−67) | +17.0 |
| AN11337.3 | No informative BLAST hits | +13.8 |
| AN8124.3 | Cryptococcus neoformans var. neoformans membrane protein (XP_572852; 7e−78) | +12.9 |
| AN6274.3 | Neosartorya fischeri short-chain dehydrogenase (XP_001264016; 9e−125) | +11.8 |
| AN6693.3 | No informative BLAST hits | +9.8 |
| AN2683.3 | Aspergillus clavatus integral membrane protein (XP_001274701; 6e−99) | +9.5 |
| AN8647.3 | Neosartorya fischeri formate/nitrite transporter, putative (XP_001262468; 8e−121) | +9.3 |
| AN1659.3 | Aspergillus terreus amino acid permease INDA1 (XP_001214474; 0.0) | +8.6 |
| AN11574.3 | No informative BLAST hits | +8.3 |
| AN0726.3 | Neosartorya fischeri SUN domain protein Adg3, putative (XP_001264362; 1e−136) | +8.0 |
| Down-regulated genes | ||
| AN3032.3 | Aspergillus clavatus cell surface protein, putative (XP_001270917; 9e−14) | −5.9 |
| AN4819.3 | A. nidulans FluG | −5.0 |
| AN6794.3 | No informative BLAST hits | −4.8 |
| AN8006.3 | A. nidulans DewA hydrophobin | −4.3 |
| AN6368.3 | Aspergillus fumigatus arginyl-tRNA synthetase (XP_755736; 0.0) | −4.2 |
| AN7540.3 | Aspergillus fumigatus eukaryotic translation initiation factor 3 subunit EifCd (XP_755799; 0.0) | −3.4 |
| AN5155.3 | Neosartorya fischeri tRNA-specific adenosine-34 deaminase subunit Tad3, putative (XP_001264959; 9e−122) | −3.2 |
| AN3800.3 | No informative BLAST hits | −3.1 |
| AN4770.3 | Phosphoadenosine phosphosulfate reductase | −3.1 |
| AN8269.3 | Aspergillus terreus heat shock protein 82 (XP_001216617; 0.0) | −3.0 |
a
BLASTX searches were used for genes designated “hypothetical” in the A. nidulans genome database (Broad Institute). Genes with E values of >1e−5 are designated “No informative BLAST hits.”
b
Derived from the mean of two biological replicates.