TABLE 2.
Genes isolated from the genetic screen that inhibit the growth of sec14ts cki1 cells
| Gene/ORFa | Description |
|---|---|
| STE20/YHL007C | Cdc42p-activated signal-transducing protein kinase that regulates polarized growth |
| ARK1/YNL020C | Serine/threonine protein kinase involved in regulation of the cortical actin cytoskeleton |
| CDC43/YGL155W | Beta subunit of geranylgeranyltransferase type I that has substrates important for morphogenesis |
| TIP1/YBR067C | Major cell wall mannoprotein with possible lipase activity |
| CLB5/YPR120C | B-type cyclin involved in DNA replication during S phase; activates Cdc28p |
| SEO1/YAL067C | Putative permease, member of the allantoate transporter subfamily of the major facilitator superfamily |
| GLC8/YMR311C | Regulatory subunit of protein phosphatase 1 Glc7p |
a
ORF, open reading frame.