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. 2007 Oct 22;335(7625):869. doi: 10.1136/bmj.39339.448819.AE

Table 3.

 Incidence of important adverse reactions in first 24 hours

Allocated intervention Type of reaction Time after administration (hours:minutes) Treatment*
Haloperidol (10 mg) Acute dystonia 0:15 Promethazine (50 mg)
Haloperidol (10 mg) Acute dystonia 0:33 Promethazine (50 mg)
Haloperidol (10 mg) Acute dystonia 1:20 Promethazine (50 mg)
Haloperidol (10 mg) Acute dystonia 1:50 Promethazine (50 mg)
Haloperidol (10 mg) Acute dystonia 15:00 Promethazine (50 mg)
Haloperidol (5 mg) Acute dystonia 15:30 Promethazine (50 mg)
Haloperidol (10 mg) Acute dystonia 18:20 Promethazine (50 mg)
Haloperidol (5 mg) Acute dystonia 20:45 Promethazine (50 mg)
Haloperidol (5 mg) Acute dystonia 22:50 Diazepam (10 mg) plus promethazine oral (25 mg)
Haloperidol (10 mg) Acute dystonia plus seizure 0:30 Diazepam (10 mg) plus promethazine (50 mg)
Haloperidol (10 mg) Seizure 16:55 Diazepam (10 mg)
Haloperidol (5 mg) plus promethazine (25 mg) Seizure 1:30 Clonazepam oral (2 mg)

*Intramuscular unless stated otherwise.