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. 2007 Nov;171(5):1629–1639. doi: 10.2353/ajpath.2007.070221

Figure 6.

Figure 6

Quantitative RT-PCR analysis of normal skin (basal), epithelial tumors, and spindle cell tumors from +/+ and Snai2-null mice revealed differing patterns of expression for Snai1 and Snai2 in epithelial and spindle cell tumors of +/+ and Snai2-null mice. A: Snai2 expression was significantly higher in epithelial and spindle cell tumors than in normal skin of +/+ mice. *P < 0.04. Snai2 expression was also significantly higher in epithelial than in spindle cell tumors of these mice. #P < 0.05. Expression of Snai2 was not evaluated in Snai2-null mice. B: Snai1 expression was significantly higher in Snai2-null spindle cell tumors than in normal skin from Snai2-null mice. *P < 0.05. Snai1 expression was significantly higher in epithelial tumors of Snai2-null mice than in epithelial tumors of +/+ mice. *P < 0.03. In addition, there was significantly increased expression of Snai1 in spindle cell tumors of both +/+ and Snai2-null mice compared with epithelial tumors in the same genotype. #P < 0.03.