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MPs isolated from human atherosclerotic plaque activate the release of TNFR-1, ICAM-1, and EPCR from HUVECs. HUVECs were incubated with MPs as described in Materials and Methods. Release in the culture medium of TNFR-1 (A) (values are mean ± SD, n = 12, each in duplicate), ICAM-1 (B) (values are mean ± SD, n = 3, each in duplicate), and EPCR (C) (values are mean ± SD, n = 8, each in duplicate). Significance of MP and TMI-2 effects was calculated by t-test (Mann-Whitney U-test).
