Table 3.
Strain | Key alleles | Mutation rate* × 109 | Relative rate† |
---|---|---|---|
DBY747 | Wild type | 7.0 ± 4.4 | 1 |
SBU | mms2 | 216.6 ± 50.0 | 31.0 |
WXY9382 | rev3Δ | 8.7 ± 5.0 | 1.2 |
SBUr3L | mms2 rev3Δ | 8.7 ± 5.0 | 1.2 |
All strains are isogenic and carry the revertable trp1-289 amber mutation. Rates are expressed as number of revertants per cell per generation. The results shown are the mean ± SD of five (DBY747 and SBU) or three (WXY9382 and SBUr3L) sets of experiments.
Relative to the wild-type strain.