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. 1988 Dec;54(12):3180–3182. doi: 10.1128/aem.54.12.3180-3182.1988

Toxin profiles of Vibrio cholerae non-O1 from environmental sources in Calcutta, India.

G B Nair 1, Y Oku 1, Y Takeda 1, A Ghosh 1, R K Ghosh 1, S Chattopadhyay 1, S C Pal 1, J B Kaper 1, T Takeda 1
PMCID: PMC204448  PMID: 3223774

Abstract

A collection of Vibrio cholerae non-O1 isolated from the aquatic environs of Calcutta, a cholera-hyperendemic area, were examined for the production of cholera toxin (CT), Shiga-like toxins (Vero toxins), heat-stable enterotoxin, and hemolysins. Two (0.5%) V. cholerae non-O1 isolates produced CT. The DNA from both these isolates also hybridized with a DNA probe containing sequences encoding the A subunit of CT. None of the strains produced Shiga-like toxins or heat-stable enterotoxin. Hemolytic activity was observed in 89.7% of the strains, of which 36.1% exhibited biological activity in the suckling mouse. However, none of them produced a hemolysin that cross-reacted with the thermostable direct hemolysin of Vibrio parahaemolyticus. It appears from this study that a small percentage of environmental V. cholerae non-O1 strains do possess the potential for causing cholera-like diarrhea.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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