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. 2007 May 30;14(8):959–968. doi: 10.1128/CVI.00123-07

FIG. 5.

FIG. 5.

BKV-specific antibody titers and cellular immune response in KT patients with PVAN. Left panels show plasma BKV load (black line, log/ml, left y axis) and antibody activity (OD at 492 nm, right y axis) for anti-VP1 (brown lines) (IgG, solid circles; IgM, open circles), anti-LT antigen (blue lines) (IgG, solid diamonds; IgM, open diamonds), and anti-agnoprotein (green lines) (IgG, solid triangles; IgM, open triangles) as well as the time points (×) of ESAs. Right panels show IFN-γ ESAs after stimulation with LT antigen peptides (blue bars), VP1 peptides (brown bars), and agnoprotein peptides (green bars) at the time points indicated in the left panels. (A) Patient 1 (49-year-old female), with definitive PVAN diagnosed at 7 weeks posttransplant. (B) Patient 2 (54-year-old male), with definitive PVAN at 5 weeks posttransplant. (C) Patient 3 (53-year-old male), with definitive PVAN at 9 weeks posttransplant.