FIGURE 10. Insulin tolerance testing of wild-type and iPLA2β-null mice that had been maintained on normal chow or a high fat diet.
Wild-type (closed squares) or iPLA2β-null (closed circles) mice were fed a normal mouse chow diet after weaning until they were 8 weeks of age and were then fed a high fat diet for the next 6 months. Intraperitoneal insulin tolerance testing was then performed after an overnight fast. Values represent mean ± S.E. (n = 24). A single asterisk denotes p < 0.02, and a double asterisk denotes p < 0.002 versus wild-type.