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T-cell-independent antibody responses in E. muris-immunized mice. OMP-19 antibody titers were measured in sera of E. muris-immunized wild-type, MHC class II-, and CD4-deficient mice. Differences in titers between wild-type and gene-targeted strains were statistically significant, except where indicated (n.s.) (Mann-Whitney test with 99% confidence interval; P < 0.05).
