Figure 2.
Acute ethanol intoxication exerts a dose-dependent inhibition of IFN- γ mRNA in the lung. Mice were administered 1.5g/kg, 3.0g/kg ethanol or PBS i.p. 30 minutes prior to i.t. injection with 10 μg LPS. Animals were sacrificed at indicated time points and whole lung IFN-γ mRNA measured by real-time RT-PCR. * p <0.05 compared to PBS control group at same time point. † p <0.05 vs. 3.0 g/kg ethanol at same time point. n= 4 to 7 per time point for each treatment group.