Figure 3.
IFN-γ is necessary for maximal MIG, IP-10, and I-TAC induction in response to i.t LPS. IFN-γ -/- and C57BL/6 background control mice received 10 μg i.t. LPS and sacrificed at indicated time points. Whole lung MIG (Fig. 3a), IP-10 (Fig. 3b), and I-TAC (Fig. 3c) mRNA responses were measured by RT-PCR. * p <0.05 vs. background control strain at same time point. n=5 per time point per strain.