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Fig. 6. Lsh deficiency raises trimethylated H3-K4 at pericentromeric regions. (A) Lsh-deficient and wild-type MEFs are double stained for detection of trimethylated H3-K4, HP1 and counterstained with Dapi. (B) Lsh-deficient and wild-type MEFs are treated with colcemid and the metaphase spread immunostained for detection of dimethylated H3-K4 and counterstained with DAPI.
