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. Author manuscript; available in PMC: 2007 Oct 29.
Published in final edited form as: Neuroimage. 2006 Nov 27;34(3):905–923. doi: 10.1016/j.neuroimage.2006.09.046

Figure 10. Prefrontal connections with the amygdala overlap with the neurochemical classes of calbindin (CB) and parvalbumin (PV) positive inhibitory neurons in prefrontal cortices.

Figure 10

A, Axonal terminals from the amygdala (green fibers) predominantly overlapped with CB positive interneurons (red neurons) in layers 2 and superficial part of layer 3. B, There was little overlap of axons from the amygdala and CB positive interneurons in the middle layers (deep part of layer 3, layer 4, or upper part of layer 5). C-E, PV-positive interneurons (red) were found mostly in the middle layers (deep part of layer 3, layer 4, and superficial part of 5). Projection neurons directed to the amygdala (green neurons, arrows) were surrounded by both CB (B) and PV (D) positive interneurons in the middle layers. Projection neurons (green) in the deep layers were mostly surrounded by PV (red) positive interneurons (E). Inset (bottom left) shows the site (box) where samples from A-E were captured through the depth of the cortex (area 32).