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. Author manuscript; available in PMC: 2008 Oct 1.
Published in final edited form as: Gene. 2007 Jun 7;400(1-2):44–51. doi: 10.1016/j.gene.2007.05.017

Fig. 2.

Fig. 2

Activation of a luciferase reporter gene containing the TSHβ gene promoter (black boxes) by normal and mutant LHX3 protein isoforms. The indicated PIT1, LHX3a (panel A), LHX3b (panel B) or control expression vectors were transiently co-transfected into mouse pituitary GHFT1 cells. Promoter activity was assayed by measurement of luciferase activity after 48 hours. Activities are mean [light units/10 seconds/μg total protein] of triplicate assays ± S.E.M. WT = wild type.