TABLE 3.
Compounds used throughout this study
| Substrate | Chemical name | Product(s)a |
|---|---|---|
| IEOT | 2-(N-Ethylamino)-4-hydroxy-6-(N-isopropylamino)-1,3,5-triazine | IOOT, EOOT |
| MMOT | 2,4-Dimethylamino-6-hydroxy-1,3,5-triazine | MOOT |
| EEOT | 2,4-Diethyamino-6-hydroxy-1,3,5-triazine | EOOT |
| IIOT | 2,4-Diisopropylamino-6-hydroxy-1,3,5-triazine | IOOT |
| (iB)2OT | 2,4-Di(N-isobutylamino)-6-hydroxy-1,3,5-triazine | (iB)OOT |
| (sB)2OT | 2,4-Di(N-secbutylamino)-6-hydroxy-1,3,5-triazine | (sB)OOT |
| (tB)2OT | 2,4-Di(N-terbutylamino)-6-hydroxy-1,3,5-triazine | (tB)OOT |
| EMOT | 4-(N-Ethylamino)-6-hydroxy-2-(N-methylamino)-1,3,5-triazine | EOOT, MOOT |
| IMOT | 6-Hydroxy-4-(N-isopropylamino)-2-(N-methylamino)-1,3,5-triazine | IOOT, MOOT |
| AAOT | 2,4-Diamino-6-hydroxy-1,3,5-triazine | AOOT |
| EAOT | 2-Amino-6-(N-ethylamino)-4-hydroxy-1,3,5-triazine | EOOT, AOOT |
| IAOT | 2-Amino-4-hydroxy-6-(N-isopropylamino)-1,3,5-triazine | IOOT, AOOT |
| (oE)2OT | 2-Hydroxy-4,6-di(N-hydroxyethylamino)-1,3,5-triazine | (oE)OOT |
| (oE)EOT | 2-(N-Ethylamino)-4-hydroxy-6-(N-hydroxyethylamino)-1,3,5-triazine | (oE)OOT, EOOT |
| (oE)AOT | 2-Amino-4-Hydroxy-6-(N-hydroxyethylamino)-1,3,5-triazine | (oE)OOT, AOOT |
| I(3MoP)OT | 2-Hydroxy-4-(N-isopropylamino)-6-N-(3-methoxypropylamino)-1,3,5-triazine | (3MoP)OOT, IOOT |
| (EM)EOT | 2-(N-ethyl-N-methylamino)-4-ethylamino-6-hydroxy-1,3,5-triazine | EOOT |
| CAOT | 2-Amino-4-chloro-6-hydroxy-1,3,5-triazine | AOOT |
| CEOT | 2-Chloro-4-(N-ethylamino)-6-hydroxy-1,3,5-triazine | EOOT |
| CIOT | 2-Chloro-4-hydroxy-6-(N-isopropylamino)-1,3,5-triazine | IOOT |
| BBOT | 2,4-Di(N-Butylamino)-6-hydroxy-1,3,5-triazine | NS |
| AOOT | 2-Amino-4,6-dihydroxy-1,3,5-triazine | NS |
| MOOT | 2,4-Dihydroxy-6-(N-methylamino)-1,3,5-triazine | NS |
| EOOT | 2,4-Dihydroxy-6-(N-ethylamino)-1,3,5-triazine | NS |
| IOOT | 2,4-Dihydroxy-6-(N-isopropylamino)-1,3,5-triazine | NS |
| OOOT | 2,4,6-Trihydroxy-1,3,5-triazine | NS |
| (MM)2OT | 2,4-Bis(dimethylamino)-6-hydroxy-1,3,5-triazine | NS |
| (EE)MOT | 2-Diethylamino-4-methylamino-6-hydroxy-1,3,5-triazine | NS |
| (EE)EOT | 2-Diethylamino-4-ethylamino-6-hydroxy-1,3,5-triazine | NS |
| (Mo)2OT | 2,4-Dimethoxy-6-hydroxy-1,3,5-triazine | NS |
| C(MM)OT | 2-Chloro-4-dimethylamino-6-hydroxy-1,3,5-triazine | NS |
| CIET | 2-Chloro-4-(N-ethylamino)-6-(N-isopropylamino)-1,3,5-triazine | NS |
| CEET | 2-Chloro-4,6-di(N-ethylamino)-1,3,5-triazine | NS |
| CIIT | 2-Chloro-4,6-di(N-isopropylamino)-1,3,5-triazine | NS |
| FIET | 2-Fluoro-4-(N-ethylamino)-6-(N-isopropylamino)-1,3,5-triazine | NS |
| (N3)IET | 2-Azido-4-(N-ethylamino)-6-(N-isopropylamino)-1,3,5-triazine | NS |
| (CN)IET | 2-Cyano-4-(N-ethylamino)-6-(N-isopropylamino)-1,3,5-triazine | NS |
| (OMe)IET | 2-Methoxy-4-(N-ethylamino)-6-(N-isopropylamino)-1,3,5-triazine | NS |
| (SMe)IET | 2-Methylthiol-4-(N-ethylamino)-6-(N-isopropylamino)-1,3,5-triazine | NS |
| (NH2)IET | 2-Amino-4-(N-ethylamino)-6-(N-isopropylamino)-1,3,5-triazine | NS |
| SIET | 2-Ethylamino-4-mercapto-6-isopropylamino-1,3,5-triazine | NS |
| Cyanazine | 2-Chloro-4-ethylamino-6-methylpropionitrile-1,3,5-triazine | NS |
| EEMT | 2,4-Diethylamino-6-methyl-1,3,5-triazine | NS |
| HAAT | 2,4-Diamino-1,3,5-triazine | NS |
| IEHT | 2-(N-Ethyamino)4-(N-isopropylamino)-1,3,5-triazine | NS |
| AO(MT) | 2-Amino-4-hydroxy-6-methyl-1,3,5-triazine | NS |
| AO(PT) | 2-Amino-4-hydroxy-6-propyl-1,3,5-triazine | NS |
| AOOP | 2,4-Diamino-6-hydroxy-1,3-pyrimidine | NS |
| NOOP | 4,6-Dihydroxy-5-nitro-1,3-pyrimidine | NS |
| SOOP | 4,6-Dihydroxy-2-mercapto-1,3-pyrimidine | NS |
| OOOP | 2,4,6-Trihydroxy-1,3-pyrimidine | NS |
a
NS, not a substrate for AtzB.