Figure 5.

Phylogenetic tree of hepadnaviruses. The consensus phylogenetic tree was based on nucleotide sequences from the core and surface genes of human, chimpanzee, gibbon, woolly monkey, and woodchuck HBV isolates. Distance along the horizontal axis among isolates is proportional to genetic divergence. The scale at the bottom represents 5% divergence. The genotypes (A–F) of the human HBV isolates are given in parentheses. The GenBank accession numbers for the various isolates are given in Materials and Methods.