. 2007 Jul 25;45(9):3095–3097. doi: 10.1128/JCM.00643-07

TABLE 1.

Resistance patterns of RMP-resistant M. tuberculosis isolates by proportion method, LiPA, and DNA sequencing

Patient	Strain	Isolation date (day/mo/yr)	Drug resistance shown by proportion method	Mutation shown by:
Patient	Strain	Isolation date (day/mo/yr)	Drug resistance shown by proportion method	LiPA	Sequencing^a
1	10603	21/12/2004	INH, RMP, SM	ΔS5	S531W
	5585	12/05/2005	INH, RMP, SM, EMB	ΔS5	S531W
	4522	12/07/2006	INH, RMP, SM, EMB	ΔS5	S531W
2	15	03/01/2006	INH, RMP	R5^b	S531L
	3267	28/04/2006	INH, RMP	R5	S531L
3	9796	25/11/2005	INH, RMP, EMB, SM	ΔS4/ΔS5	H526C/S531A
	1409	28/02/2006	INH, RMP, EMB, SM	ΔS4/ΔS5	H526C/S531A
4	2603	03/03/2006	INH, RMP	R5	S531L
5	9742	23/11/2005	INH, RMP, SM, CIP	ΔS4/ΔS5	H526C/S531A
6	4164	29/05/2006	INH, RMP, EMB	ΔS5	S531W

Sequencing mutation descriptions are as follows: first, the amino acid residue in the wild-type sequence, then the codon position, and finally the amino acid residue in the mutated sequence. The numbering system is based on the Escherichia coli β-subunit of RNA polymerase (25).

R5, S531L.