TABLE 1.

Predicted specificities and sensitivities of the probes for H. pylori detection^a

Probeb	Type	Specificity (%)c	Sensitivity (%)d	Fluorescence (%)	Reference(s)
HP16S-1	DNA	82	82	41-60	19
Hpy-1	DNA	86	95	0-5	5a, 8a, 23, 23a
Hprobe	PNA	100	25	6-20	4, 25a
Hpy769	PNA	85	89	6-20	This work

^aEstimation of binding affinity through fluorescence intensity was based on the work of Fuchs et al. (10).

^bSequences are as follows: HP16S-1, 5′-GGA GTA TCT GGT ATT AAT CAT CG-3′; Hpy-1, 5′-CAC ACC TGA CTG ACT ATC CCG-3′; Hprobe, 5′-TAATCAGCACTCTAGCAA-3′. The sequence of Hpy769 is given in the text.

^cCalculated as (number of H. pylori strains detected by the probe)/(total number of bacterial strains detected by the probe) × 100.

^dCalculated as (number of H. pylori strains detected by the probe)/(total number of H. pylori strains in the databases) × 100.