TABLE 3.

Numbers of hGISA isolates detected using vancomycin and/or teicoplanin population analysis profiling and breakdown into hVISA, hTISA, and hVISA and hTISA

Group	No. of isolates investigated by PAP	No. of hGISA isolates detected
		vPAP-AUC	tPAP	Total hGISA	hVISAc	hTISAd	hVISA and hTISA
1a	139	73	95	108	13	35	60
2b	119	17	70	70	0	53	17
Total	258	90	165	178	13	88	77

^aGroup 1 includes isolates exhibiting Etest macromethod values of ≥8 mg/liter for vancomycin and teicoplanin or ≥12 mg/liter for teicoplanin alone.

^bGroup 2 includes additional isolates requiring PAP when the teicoplanin Etest macromethod cutoff value was decreased to 8 mg/liter.

^chVISA is defined as isolates with vPAP-AUC ratios ranging from 0.9 to 1.29.

^dhTISA is defined as isolates with resistant subpopulations capable of growth at >8 mg of teicoplanin/liter.