TABLE 4.

Evaluation of six agar screening methods to detect hGISA and isolates yielding positive Etest macromethod values

Method	Determined value (%)a
	hGISA				Etest macromethod (approach 1)b				Etest macromethod (approach 2)c
	Sens	Spec	PPV	NPV	Sens	Spec	PPV	NPV	Sens	Spec	PPV	NPV
MHT50.5	66	82	89	61	59	85	95	47	58	91	95	42
MHT52.0	98	53	77	95	95	60	85	84	96	73	91	84
MHT5S	100	6	63	100	99	6	71	75	99	7	76	75
BHIT50.5	100	57	79	100	98	70	88	95	99	84	95	95
BHIT52.0	100	18	66	100	100	23	75	100	100	27	80	100
BHIT5S	100	4	63	100	100	6	71	100	100	7	77	100

^aSens, sensitivity; Spec, specificity; PPV, positive predictive value; NPV, negative predictive value.

^bValues for detecting isolates with Etest macromethod values of ≥8 mg/liter for vancomycin and teicoplanin or ≥12 mg/liter for teicoplanin alone.

^cValues for detecting isolates with Etest macromethod values of ≥8 mg/liter for teicoplanin alone.