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. 2007 Jul 3;81(18):9999–10008. doi: 10.1128/JVI.00592-07

FIG. 6.

FIG. 6.

Point mutations near the C terminus of gp41 reduce the dependence of HIV-1 fusion on particle maturation. (A) Mature and immature BlaM reporter particles bearing the indicated mutant Env proteins were assayed for fusion with SupT1 cells. The fusion of mature (filled symbols) and immature (open symbols) HIV-1 particles was expressed as the blue/green fluorescence ratio per nanogram of p24 in the inoculum. (B) Calculation of the ratio of the fusion of mature and immature particles. Shown are mean values and standard deviations from three independent experiments.