FIG. 3.

Similar HIV-1 transcriptional activity in resting and activated CD4⁺ T cells from treated and untreated patients. (A) Frequencies of HIV RNA⁺ cells in resting (RST) and activated (ACT) CD4⁺ T cells normalized to 10⁶ cells of the corresponding cell types. (B) Geometric means of HIV RNA contents per cell in RST and ACT CD4⁺ T cells normalized to numbers of HIV RNA⁺ cells. Analyses comprised one data point per visit, resulting in duplicate measurements for PBMC and CD4⁺ T cells for all patients except for patients 03, 08, and 11. Results of nonparametric paired analyses of CD4⁺ versus CD4⁻/CD8⁻ T cells using Wilcoxon signed-rank testing are indicated by P values.