FIG. 6.

Uniform distribution of HIV-1 env quasispecies in plasma and CD4⁺ and CD4⁻/CD8⁻ T cells. Neighbor-joining phylogenetic tree of env C2-V3-C3 sequences obtained from patients 05 and 06 constructed using MEGA 3.1. Single molecular clones (mean n = 14; range, 5 to 16) were obtained from plasma RNA, from CD4⁺ T cells (CD4⁺; total RNA and total DNA), and from CD4⁻/CD8⁻ T cells (DN [double negative]; total RNA, vRNAex, and total DNA). Symbols indicate individual clones and numbers above branches show bootstrap values. Mean diversities for each cell type are indicated.