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nsp7 to nsp10 cleavage sites for wild-type MHV and deletion mutants
| Protein | Amino acid sequence of indicated cleavage site
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| P5 | P4 | P3 | P2 | P1 | P1′ | P2′ | P3′ | P4′ | P5′ | |
| Wild type | ||||||||||
| nsp6-nsp7 | V | S | Q | I | Q | S | R | L | T | D |
| nsp7-nsp8 | L | Q | A | L | Q | S | E | F | V | N |
| nsp8-nsp9 | T | V | V | L | Q | N | N | E | L | M |
| nsp9-nsp10 | T | V | R | L | Q | A | G | T | A | T |
| nsp10-nsp11 | G | S | Q | F | Q | S | K | D | T | N |
| Mutant | ||||||||||
| Δnsp7 | V | S | Q | I | Q | S | E | F | V | N |
| Δnsp8 | L | Q | A | L | Q | N | N | E | L | M |
| Δnsp9 | T | V | V | L | Q | A | G | T | A | T |
| Δsnp10 | T | V | R | L | Q | S | K | D | T | N |
