TABLE 4.
Titers of cross-neutralizing antibodies induced by H7 subtype viruses in postinfection mouse sera
| Virus (subtype) | Titers of mouse antisera raised against indicated virusa:
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| NL/03 | EG/63 | RK/34 | QL/95 | OR/71 | UT/95 | NC/93 | BC/04 | CH/02 | VA/02 | |
| A/Netherlands/219/03 (H7N7) | 453 | 10 | 50 | 40b | 16b | 20b | 254b | 20b | 63b | 7b |
| A/tk/England/63 (H7N3) | 254 | 202 | 16b | 63 | 40b | 28b | 127b | 25b | 101b | 10b |
| A/Rostock/34 (H7N1) | 254 | 127 | 160 | 57 | 25b | 28b | 453 | 16b | 99b | 7b |
| A/ck/Queensland/95 (H7N3) | 127 | 202 | 50 | 226 | 127b | 226 | 202b | 254 | 113b | 8b |
| A/tk/OR/71 (H7N3) | 640 | 905 | 160 | 403 | 1280 | 1016 | 2032 | 1016 | 453 | 160 |
| A/tk/UT/95 (H7N3) | 254 | 320 | 40b | 202 | 403 | 320 | 640 | 320 | 226b | 50b |
| A/rhea/NC/93 (H7N1) | 1016 | 320 | 202 | 160 | 254b | 254 | 1613 | 320 | 50b | 50b |
| A/ck/BC/CN-7/04 (H7N3) | 640 | 226 | 57 | 113 | 254b | 320 | 640 | 254 | 160b | 28b |
| A/ck/Chile/02 (H7N3) | 806 | 320 | 101 | 226 | 202b | 202 | 806 | 113 | 1016 | 25b |
| A/tk/VA/02 (H7N2) | 160 | 127 | 50 | 101 | 254b | 160 | 806 | 226 | 226b | 320 |
a
Mouse antisera were collected at 28 dpi for VA/02 and RK/34 viruses and at 56 dpi for the remaining eight viruses. Postinfection sera from three or four mice were pooled and used in the MN assay. Homologous neutralization titers are indicated in boldface.
b
Neutralization titers that are fourfold or lower than the homologous titers.