TABLE 1.
Preinfecting virus | Cat no. | Age at challenge (mo) | RNA copies/ml of plasmaa | DNA copies/mg of PBMC DNAb | Infectious units in 106 PBMC | CD4+ T lymphocytes/ml of bloodc |
---|---|---|---|---|---|---|
FIVPET | 2682 | 72 | 2,000 | 3,000 | 1 | 690 |
3552 | 72 | 6,100 | 4,200 | 10 | 200 | |
3608 | 72 | 3,300 | 7,600 | 1 | 300 | |
3633 | 72 | 11,300 | 1,900 | 10 | 440 | |
3646 | 72 | 17,900 | 10,000 | 1 | 398 | |
FIVM2 | 2646 | 57 | 2,100 | 34,100 | 10 | 250 |
2647 | 57 | 5,000 | 62,000 | 100 | 210 | |
2658 | 57 | 9,000 | 84,700 | 100 | 326 | |
2664 | 57 | 20,000 | 87,600 | 100 | 230 | |
2668 | 57 | 28,000 | 98,300 | 100 | 408 | |
FIVχd | 2839 | 36 | 6,000 | 2,600 | 10 | 800 |
2841 | 36 | 700 | 900 | 1 | 910 | |
2893 | 36 | 3,000 | 800 | 10 | 870 | |
3335 | 36 | 3,200 | 1,000 | 1 | 980 | |
3437 | 36 | 900 | 1,900 | 1 | 700 | |
2731 | 36 | 1,400 | 800 | 10 | 700 | |
2881 | 36 | 800 | 700 | 1 | 700 | |
2884 | 36 | 6,500 | 5,100 | 1 | 800 | |
2897 | 36 | 800 | 2,000 | 10 | 500 | |
3316 | 36 | 2,000 | 3,000 | 1 | 760 |
RNA copies determined with the appropriate RT-PCR-specific assay.
DNA copies determined with the appropriate PCR-specific assay.
Normal range, 1,000 to 3,500.
The first five animals in this group were challenged with FIVPET, the others with FIVM2.